Moringa oleifera leaves have been reported to possess potential hypotensive and hypocholesterolemic andhypoglycemic activities; nevertheless toxicological data of this herb in animal models have still been scanty. Theobjective of this study was to evaluate both acute and chronic toxicity of the water extract of m. Oleifera leaves by oraladministration. Acute toxicity test in mice by gavage with the extract twice, each at the dose of 10 g/kg, revealed thatthe extract produced no acute toxic symptoms and gross lesions of vital organs. Chronic toxicity study wasinvestigated in eighty wistar rats allocated into four groups, each of ten per sex. Group 1 was the control groupreceiving distilled water.
According the revision by stohs and hartman ( 2015 ), until this date none of the human, in vitro studies, or extrapolations of animal studies to humans, reported adverse effects with doses of m. Oleifera leaves and leaf extracts achievable by oral ingestion. Although, there was not any report of major adverse side effects, there are some important information that should be registered. In fact, there are some studies suggesting that m. Oleifera cannot be used in combination with other modern medicines in humans. A research by gholap et al. ( 2004 ) concluded that m. Oleifera has been noted to be a good regulator of insulin.
This review mainly provides a systematic summary, focusing on the botanical and traditional uses, as well as the phytochemistry, pharmacology, toxicity and agricultural economy and dietary benefit aspects of m. Oleifera. This review highlights the promising biological activities of m. Oleifera, including anti-inflammatory, antioxidant, anti-tumour, hepatoprotective and immunomodulatory effects, which have attracted much attention. Although some pharmacological activities are not associated with the traditional uses of the plant, they could still provide valuable clues and be further developed. Animal experiments revealed that the toxicity of m. Oleifera was limited to the liver, kidney and blood and also indicated that an overdose may result in genetic toxicity.
4. Moringa oleifera May Reduce Inflammation
Lin zhang2,3* 1department of obstetrics and gynecology, west china second university hospital of sichuan university and the key laboratory of birth defects and related diseases of women and children, ministry of education, sichuan university, chengdu, china 2laboratory of molecular translational medicine, center for translational medicine, key laboratory of birth defects and related diseases of women and children (sichuan university), ministry of education, west china second university hospital, sichuan university, chengdu, china 3department of forensic genetics, west china school of basic medical sciences & forensic medicine, sichuan university, chengdu, china 4department of geriatrics, chengdu second people’s hospital, chengdu, china moringa oleifera lam. , a plant native to tropical forests of india, is characterized by its versatile application as a food additive and supplement therapy.
The moringa plant has been used for centuries throughout the tropics for medicinal purposes and to improve nutrition, especially in children. A fogarty-funded researcher is helping to provide the scientific evidence behind the so-called “superfood,” as well as enabling farmers to increase their moringa crop yield and improve the purity of the end product, a powdered diet supplement. A growing body of evidence suggests that moringa (moringa oleifera) helps fight inflammation, a known contributor to chronic conditions such as cancer, diabetes and obesity. Dr. Carrie waterman, a natural products chemist at the university of california, davis, secured a five-year fogarty international research scientist development award (irsda) to explore moringa’s potential.
5. Moringa Can Lower Cholesterol
Moringa oleifera (mo) is an edible plant native to asia and africa that is also cultivated around the world. The leaves and seed pods are nutritious and widely consumed as food while the bark and root are used in folk remedies for their perceived medicinal properties. Products derived from this botanical are used to treat a variety of conditions including asthma, diabetes, ulcers, infections, and cancer. In addition, the plant extracts are used in primitive water filtration systems to remove pollutants and algae (1). Preclinical studies suggest various properties with mo leaf, seed, and root extracts, including anticancer (3) (4) , hepatoprotective (10) , hypoglycemic (12) (41) , anti-inflammatory (13) (14) , antibacterial (18) (19) (42) , antifungal (20) , antiviral (21) , and antisickling (37) effects.
What Is Moringa Good For?
Phenolic compounds, antioxidant and antibacterial activities of defatted seed flour were investigated by singh et al. [ 45 ]. The results showed that extractability of phenolic compounds was significantly higher (p < 0. 05) in bound phenolic extract (4173. 00 ± 32. 22 mg gallic acid equivalents (gae)/100 g) than in free phenolic extract (780. 00 ± 14. 2 mg gae/100 g) and it showed higher antioxidant and antimicrobial activities. The ic50 value for dpph radical scavenging activity was 0. 9 ± 0. 05 and 14. 9 ± 0. 07 mg/ml for bound phenolic and free phenolic extracts, respectively.
Covid-19 is a new disease that has become a pandemic. This disease should be watched out for because transmission is relatively fast, has a mortality rate that cannot be ignored, and there is no definitive therapy. After covid 19, people will be more selective in the food they eat. The types of food chosen were those that have health benefits, especially as immunity boosters. The problem was what types of products can provide these benefits en masse, cheap, and easy to access. This review aims to explore the potential of the moringa plant as a plant that can be a source of functional food as a post-covid 19 immune booster.
Moringa oleifera, the medicinal plant in moringaceae family, has been used worldwide in traditional medicine. Different parts of this plant contain a profile of important minerals, and a good source of protein, vitamins, and various phenolics. The objective of this study was to compare the proximate composition and mineral constituents in moringa leaves from 11 different agro climatic regions distributed in thailand. These leaves were found to contain 19. 15-28. 80 % of protein; 2. 06-2. 47 % of fat; 16. 30-23. 89 % of fiber; 8. 52-13. 53 % of moisture. The calcium, potassium and iron contents of moringa leaves (100 g dry weight) were found in the range of 1510.
For maximum leaf production, the spacing of plants should be 15 x 15cm or 20 x 10cm, with conveniently spaced alleyways (for example every 4m) to facilitate farm management and harvesting. Weeding and disease prevention can be challenging because of high density. In a semi-intensive production, plants are spaced 50cm to 1m apart. This gives good results with much less maintenance. Moringa trees can also be cultivated in alleyways and associated near other crops. Distances between moringa rows in agroforestry cultivation are usually between 2 - 4m.
What Are the Side Effects of Moringa
Moringa (moringa oleifera, moringa pterygosperma) leaves contain vitamins, minerals, and essential amino acids as well as a number of glycosides. It has been used as a galactogogue in asia,[ 1 ] particularly in the philippines where it is called malunggay. Many published studies are of very poor quality. Small studies indicate that moringa might have some activity as a galactogogue in mothers of preterm infants by increasing maternal serum prolactin and milk volume. A reasonably well-conducted study found no evidence of galactogogue activity in the first 3 days postpartum among mothers of full-term infants in a baby friendly hospital.
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